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Myasthenia gravis (MG) is an archetypal autoimmune disease. The pathology is characterized by autoantibodies to the acetylcholine receptor (AChR) in most patients or to muscle‐specific tyrosine kinase (MuSK) in others and to a growing number of other postsynaptic proteins in smaller subsets. A decrease in the number of functional AChRs or functional interruption of the AChR within the muscle end plate...
Introduction
In this study we determined the clinical, paraclinical, and treatment‐related features of juvenile myasthenia gravis (JMG) as well as the clinical course in a cohort of French children.
Methods
We conducted a retrospective study of 40 patients with JMG at 2 French pediatric neurology departments from April 2004 to April 2014.
Results
Among the patients, 70% had generalized JMG, 52%...
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