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IntroductionContact heat evoked potentials (CHEPs) may be an objective, non‐invasive diagnostic tool in small‐fiber neuropathy (SFN). This study establishes normal CHEP values and examines their applicability in SFN patients. Methods: Standardized CHEPs were administered at the wrist and ankle. The N2 and P2 latencies and N2–P2 peak–peak amplitude were recorded by electroencephalography. We examined...
Introduction: We examined optimization of a temperature threshold testing (TTT) protocol for patients with suspected small‐fiber neuropathy (SFN) to lessen the burden for both patients and technicians, without sacrificing accuracy. Methods: Data from 81 patients with SFN (skin biopsy and TTT abnormal) and 81 without SFN (skin biopsy and TTT normal) were used. Warm, cold, and heat pain sensation thresholds...
Introduction: Peripheral neuropathy related to levodopa/carbidopa intestinal gel (LCIG) therapy for advanced Parkinson disease (PD) is under investigation and is debated in the literature. The purpose of the study was to detect whether small nerve fibers are damaged during LCIG infusion. Methods: Five advanced PD patients were enrolled prior to starting LCIG infusion. Six PD patients on oral levodopa...
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