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DNA‐dependent protein kinase (DNA‐PK) is a very large holoenzyme comprised of the p470 kDa DNA‐PK catalytic subunit (DNA‐PKcs) and the Ku heterodimer consisting of the p86 (Ku 80) and p70 (Ku 70) subunits. It is best known for its nonhomologous end joining (NHEJ) activity, which repairs double‐strand DNA (dsDNA) breaks (DSBs). As expected, the absence of DNA‐PK activity results in sensitivity to ionizing...
Stabilization of central carbohydrate metabolism plays a key role in plant stress response. Carbohydrates are substrate for numerous metabolic and stress‐responsive reactions and have been shown to be involved in diverse signalling processes on a whole‐plant level. Regulation of enzymatic sucrose synthesis and degradation is well‐known to be central to many stress‐related processes as it significantly...
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