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Heart failure with preserved ejection fraction (HFpEF) will soon take over as the predominant form of heart failure. This is largely driven by the continuing increased incidences of obesity and type 2 diabetes (T2D), which promote HFpEF in the absence of pressure overload stresses. With beta‐blockers showing little effectiveness in treating obesity/T2D HFpEF and with no HFpEF‐targeted drugs currently...
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