Trials is dedicated to improving the design, conduct and reporting of randomised controlled trials in health. Edited by an internationally renowned Editorial Board, we consider articles assessing aspects of the performance or findings of trials, including general trial methodology, commentaries, primary research and study protocols. With over 2 million accesses annually, we are committed to reducing waste in research by experimenting with, and refining, innovative approaches to improving communication about trials.
Trials
Description
Identifiers
e-ISSN | 1745-6215 |
Publisher
BioMed Central
Additional information
Data set: Springer
Articles
Background Poor clinical trial enrollment continues to be pervasive and is especially problematic among young adults and youth, and among minorities. Efforts to address barriers to enrollment have been predominantly focused on adult diseased populations. Because older adults may already have established attitudes, it is imperative to identify strategies that target adolescents and young adults. The...
Background In people with chronic obstructive pulmonary disease (COPD), limb-muscle dysfunction is one of the most troublesome systemic manifestations of the disease, which at the functional level is evidenced by reduced strength and endurance of limb muscles. Improving limb-muscle function is an important therapeutic goal of COPD management, for which resistance training is recommended. However,...
Background Postpartum haemorrhage remains a major cause of maternal mortality and morbidity worldwide. Active management of the third stage of labour reduces the risk of postpartum haemorrhage. Oxytocin and oxytocin/ergometrine are commonly used in the UK, with oxytocin/ergometrine being more effective at preventing moderate, but not severe, blood loss. Many guidelines specifically recommend using...