Glycoconjugate Journal publishes articles and reviews concerned with function, composition, structure, biosynthesis, degradation, interactions, recognition and chemo-enzymatic and synthesis of glycoconjugates; biochemistry, molecular biology, biotechnology, immunology and cell biology to glycoconjugates; aspects related to disease processes; structural and functional glycomics; glycoimmunology; glycovaccines; organic synthesis of glycoconjugates and the development of methodologies if biologically relevant; glycosylation changes in disease if focused on either the discovery of a novel disease marker or the improved understanding of some basic pathological mechanism, articles on the effects of toxicological agents on glycosylation, and the use of glycotherapeutics. Glycoconjugate Journal is the official journal of the International Glycoconjugate Organization, which organizes the biennial International Symposia on Glycoconjugates.
Glycoconjugate Journal
Description
Identifiers
ISSN | 0282-0080 |
e-ISSN | 1573-4986 |
DOI | 10.1007/10719.1573-4986 |
Publisher
Springer US
Additional information
Data set: Springer
Articles
Glycoconjugate Journal > 2019 > 36 > 5 > 419-428
Gangliosides altered during the pathological conditions and particularly in cancers. Here, we aimed to profile the gangliosides in breast cancer serum and propose potential biomarkers. LC-FTMS method was first used to identify all the ganglioside species in serum, then LC-MS/MS-MRM method was employed to quantitate the levels of gangliosides in serum from healthy volunteers and patients with benign...
Glycoconjugate Journal > 2019 > 36 > 5 > 399-408
Even though a vaccine that targets tumor-associated carbohydrate antigens on epithelial carcinoma cells presents an attractive therapeutic approach, relatively poor immunogenicity limits its development. In this study, we investigated the immunological activity of a fluoro-substituted Sialyl-Tn (F-STn) analogue coupled to the non-toxic cross-reactive material of diphtheria toxin197 (CRM197). Our results...
Glycoconjugate Journal > 2019 > 36 > 5 > 439-450
Organocatalytic coupling of glycosyl azides with enolates of active ketones and esters through azide-enolate [3 + 2] cycloaddition in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) furnished 1,4,5-trisubstituted-glycosyl-1,2,3-triazole derivatives in excellent yield. The reaction condition is simple and can be scaled-up.