The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
The progress in molecular biology methods allowed the definition of globin gene defects, including ßeta Thalassemia major (βTM) disorder. Translating the above definition into knowledge can help, with the aid of bioinformatics, improving medical diagnosis and severity assessment, in order to decide the most appropriate treatment. In this paper, we applied decision making trial and evaluation laboratory...
Machine learning methods are used to identify genetic biomarkers associated to complex diseases. Alzheimer's disease (AD) is a degenerative disorder that attacks the brain's neurons. Single Nucleotide Polymorphisms (SNPs) are the most common type of human genetic variation. SNPs are useful markers for disease genes. SNPs related to many common and serious diseases like AD. Discovering SNP biomarkers...
Gene set analysis involves the association of genes that are relevant in certain biological experiments to knowledge sources such as pathways and gene ontologies. The experiments can correspond to patient groups or expression changes at different time points in response to certain stimuli. In this paper, we present the web-based system WEGA to associate gene sets with knowledge sources and conduct...
Worldwide there are scientists and researchers who deal with proteins in an attempt to find valuable information about the various species of organisms present on earth. With the expansion of available biological data, analysis is a major challenge facing researchers wishing to explore the massive amount of information.
The development of high-throughput sequencing technologies has provided microbial ecologists with an efficient approach to assess bacterial diversity at an unseen depth. In the last year, various platforms have been used for such analysis particularly the Illumina MiSeq, 454 pyrosequencing GS FLX+ and PacBio sequencing platforms. However, analysing such high-throughput data is posing important computational...
Keyphrases are the keywords that provide the semantic metadata about document that represents the top concepts inside an article. Number of natural language processing (NLP) methodologies; such as text summarization, text mining and information retrieval applications, consider Keyphrase Extraction as a critical step to accomplish its tasks. This paper presents a method to extract keyphrases from abstracts...
The suffix array is an important indexing data structure for biological sequence analysis. The increasing size of genomic data necessitates the use of a computer cluster to speed up the computation. In this paper, we compare the performance of two distributed suffix array construction algorithms that can run on a computer cluster: the first is Futamura-Aluru-Kurtz algorithm and the second is Kulla-Sanders's...
In this study a computer-based model was developed to simulate the warm-up property of the low-voltage activated (LVA) L-type calcium channels. The LVA L-type calcium channel is one of two channels that mediate persistent inward currents in spinal alpha (a) motoneurons and plays an important role in integrating & modulating motor firing behaviors. This study was prompted by experimental observations...
Blood flow in the body is, in general, laminar. But various physiological and pathological conditions may cause disruption in the laminar flow and result in turbulence. Turbulent flow is characterized by non-linearity and non-homogeneity, and is, hence, regarded as a symptom of cardiovascular ailments. This study juxtaposes the flow of blood in normal and stenosed arterial blood vessels. For the purpose...
A computational framework was used to simulate the anterior Cruciate ligament (ACL) reconstructive surgeries, by virtually removing the ACL and then modeling the surgical preparation, tunnel architecture, graft pre-tensioning and fixation angle of a bone-patellar-tendon-bone autograft. To evaluate the relative influence of these surgical factors on the intraoperative joint response a global sensitivity...
Diabetes Mellitus is a serious global health concern affecting about 415 million or 8.8% of adults worldwide. Among other complications of the disease, diabetic foot ulceration (DFU) is one of the most serious, possibly leading to amputation. This study presents the design, implementation and testing of a method for predicting DFU based on dynamic pressure distribution. We recorded the dynamic plantar...
Restoration of upper limb movements for stroke recovery patients is an essential keystone in rehabilitative practices. The functional electrical stimulation (FES) systems had proved its success in restoring the movement in order to increase the ability to perform the daily living activities. In this study, we propose a Brain Computer Interface (BCI) system that controls the FES. The system is formed...
Wearable devices have garnered increased attention over the past years by the sports industry, military, and general public for everyday use. Technological advancements have enabled athletes, sports teams, soldiers, and physicians to track functional movements, workload, biometric and bio-vital markers to maximize performance and safety while minimizing the potential for injury or accidents. Wearable...
In this paper, the sensitivity of the split ring nanosandwich is studied after applying asymmetry to the structure. There are two asymmetry configurations that will be presented in this paper which include the tapered-down and the tapered-up configurations. The optical response in both configurations is studied and the sensitivity is measured at varying the asymmetry parameter. This design is characterized...
This paper presents a new radial basis function neural network (RBF-NN) thermal dose control scheme for high temperature hyperthermia tumors treatment using a single scanned focused ultrasound transducer. The developed RBF-NN controller constitutes two main advancements. First, no identified or predicted model is required to estimate the control actions. Second, robust performance of the developed...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.