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The prediction of the transmissibility of avian influenza A viruses from birds to humans is very important for the public health. Recently, two categories of molecular patterns, which were associated with the phenotype of interspecies transmission, were found to exist among avian influenza A viruses with different subtypes. In the paper, we used the similar method based on wavelet packet decomposition...
There are some known breast cancer oncogenes, and many genes have various relations with them. More susceptibility genes remain to be identified from these numerous relations. Based on the analysis of some literature, a multi-criteria evaluation model for breast cancer susceptibility gene has been constructed by reference. According to this model, we get the ranking evaluation result of alternatives...
From the recent experiments of gamma radiation and models given before, we study the dynamical model of p53 and Mdm2 regulated by p14/19ARF in population of cells. In order to study how they infect the mechanism of the negative feedback loop, we give numerical results to study the oscillatory features of p53, Mdm2 and p14/19ARF in population of cells. The dynamical model and results will help us understand...
DNA computing theories can be applied in cryptography and it is a very hopeful direction. Though still in primitive level, it applies in many fields and solved some hard problems successfully. The art of cryptography security is to make anybody can not read it by encoding message. This paper use a new way to show how cryptography works with DNA computing, it can transmit message securely and effectively...
At present, mathematic model for power grid program has more requirement, traditional method can't fulfil it. Ant colony algorithm has been successfully used to solve NP problem in many fields. In this paper, a new ant colony algorithm of improving key parameters to solve power network planning is presented. For a given power network model, this algorithm will find out the best routing path only if...
Background: Parkinson's disease (PD) is a degenerative disease of the brain that often do harm to the motor skills of patients. A disturbed gait is very common among PD patients, who are easy to fall down and may lose their functional independence. Purpose: In this paper, we extract features from the gait signals in PD patients and control subjects for the purpose of comparison and realization of...
Since Dervan first verifies the forming of three chains of DNA can be lain between and led to the peculiar cut of the target DNA in 1987, the research of three chains of DNA is developed quickly. Triple-stranded DNA can be formed readily at any location in double-stranded DNA with a homologous deoxyoligonucleotide in the presence of RecA-protein, it can utilize triple-stranded of DNA chain to solve...
In vivo 31P MRS provides non-invasive information about the chemical content of the energy metabolism in cellular level, which is important either in diagnosis or in treatment of many hepatic diseases. In this paper we applied Fisher linear discriminant analysis and quadratic discriminant analysis to classify the data samples based on 31P MRS into three types of hepatocellular carcinoma, hepatic cirrhosis...
Given an undirected graph with weights on the vertices, the maximum weight clique problem requires to find the clique of the graph which has the maximum weight. The problem is a general form of the maximum clique problem. In this paper, we encoded weight of vertex into a unique fixed length oligonucleotide segment and employed sticker model to solve the problem. The proposed method has two distinct...
DNA computing has a relatively strong computing power. The principle of complementary bases and double-stranded structure of DNA provide a guarantee for varieties of encoding and computing. In this paper, based on the DNA algorithm to the directed shortest hamilton path problem by Gao Lin, plasmid screening technology will be applied to solving the SHPP, and a special separation device will be used...
Rough set (RS) and support vector machine(SVM) have gradually been becoming hot spots in the territory of artificial intelligence, machine learning and data mining research. In this paper, RS and SVM theories have been discussed, a new hybrid RS-SVM model was proposed based on the attribute reduction of RS and the classification principles of SVM, which has been analyzed its possibility of application...
The PID controller has been used as the effective control method. The proper adjustment of the gains is of great importance to obtain the desired performance of the controller. However, it is necessary to find suitable PID gains automatically. This paper presents the modeling and control of Buck chopper type AC voltage regulator while the system is operating under uncertainty and nonlinearity. The...
A variant on the original bacterial foraging optimization (BFO) algorithm, called the cooperative bacterial foraging optimization (CBFO), is proposed in this paper. The results of various experimental studies using a suit of 4 widely used test functions have demonstrated the superiority of the proposed CBFO approach over the other three search techniques.
Through the analysis of the transit network solution of optimal path algorithm, this paper proposes the bus route optimization algorithm of DNA to consider both the shortest distance by bus and the minimum interchange, and gives a detailed biological process. It not only puts forward a new feasible algorithm for transit network optimal path search, but also provides an practical opportunity for the...
0-1 integer programming problem is an important problem in opsearch with widespread application. In this paper, a new DNA computation model based on self-assembled nanoparticle probes is presented to solve this problem. This is the first time to integrate with nanoparticle and oligonucleotides in DNA computation model. Major benefits of this method include vast parallelism, extraordinary information...
DNA computing is a bio-computing paradigm based on the specific hybridization of DNA strands. Most of DNA computing models and experiments were held in vitro. In this paper, a DNA computing paradigm in vivo is presented. A synthetic gene network is constructed by RNAi and lactose operon in living cell for solving minimum dominating set problem. This model explores further the ability to solve hard...
The codeword is the start of DNA computing, also, the important of DNA computing. The quality of the codeword directness effects the process of response middot We brief describe the theory of DNA codeword, survey many useful constraints and several models for the design of DNA sequences. Finally, we also point out the problems and research directions about encoding.
In this paper, we have analyzed the relationship among government control, diversification and corporate performance. The investigation has been performed using panel data procedure for a sample of 320 Chinese companies listed on the Shanghai stock exchange during the period from 2001 to 2006. We find that, diversification under government control has negative influence on firm performance, while...
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