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Random clusters of decoupled cells caused by cell death in diseased cardiac tissue can increase structural heterogeneity and give rise to abnormal patterns of propagation. The objective of this study was to use a 2-D 0.6 cm × 0.6 cm randomly generated model of a ventricular monolayer (LRd membrane model) (dx=dy=10 µm) to study the relationships between the underlying cardiac microstructure, the pattern...
Cardiologic magnetic resonance imaging (MRI) has recently been improved by faster acquisition and higher resolution hardware. Commercially available MRI equipment is able to capture contrast agents with the needed time and space definition to map myocardial viability. MRI myocardial imaging has an emerging role in cardiology studies, and it has experienced a crescent relevance in clinical investigations...
T-wave alternans (TWA ) amplitude is an index of risk for arrhythmic events. It increases with heart rate (HR) so that its evaluation is often performed under exercise. This study aims to investigate if TWA rate of change with HR can be also used for risk assessment. Our HR adaptive match filter for automatic TWA identification was applied to exercise ECG recordings of 266 ICD patients, 76 of which...
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