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Falls of patients are an important issue in hospitals, it causes severe injuries to the patients, increases hospitalization time and treatment costs. The detection of a fall, in time, provides faster rescue to the patient, preventing more serious injuries, as well as saving nursing time. The MovinSense® is an electronic device designed for monitoring patients to prevent pressure sores, and the main...
This dissertation objective is to contribute for the development of a robotic system towards neurosurgery assistance in Deep Brain Stimulation (DBS) stereotactic procedures. Being DBS neurosurgery typically a long, physically and cognitively demanding procedure; the introduction of a robotic assistant to hold, manipulate and position instrumentation would improve the medical team working conditions...
Determine blood type is essential before administering a blood transfusion, including in emergency situation. Currently, these tests are performed manually by technicians, which can lead to human errors. Various systems have been developed to automate these tests, but none is able to perform the analysis in time for emergency situations. This work aims to develop an automatic system to perform these...
An approach to Parkinson's Disease's (PD) tremor suppression based on a self-tunable Dynamic Vibration Absorber (DVA) was studied in this research, where two configurations, differed by a damping element, were addressed.
Oxygen saturation is a key parameter for assessing a patient condition. The present work aims to develop a stand-alone pulse oximeter and photoplethysmographic system. In addition, it incorporates a force sensor and a set of accelerometers to measure the contact force and the finger height offset relatively to the heart. Both the design of hardware and the development of firmware are presented. Currently,...
Functional electrical stimulation is an important tool towards rehabilitation of lost motor functions on individuals who have had spinal cord injury or stroke. Peripheral nerves are preferential targets for electrical stimulation because of easy surgical access, whereelectrodes serve as interfaces between neuroprostheses and the peripheral nerve. The selection of an electrode is a trade-off between...
The research team has been focused, in the last years, on lab-on-a-chip devices for clinical applications, where the acoustic streaming technique is used for promoting the mixing, the pumping and the chemical reactions of fluids inside the microstructures. This paper describes an overview of the advances achieved by the group in the modeling and simulation areas. In particular, it is focused the modeling...
The final goal of this work is to develop an corneal microscope based on fluorescence lifetime imaging microscopy (FLIM) of the metabolic co-factor FAD. In several corneal pathologies metabolic alterations occur prior to the pathologic expression therefore the assessment of corneal cells metabolic state could be a great advantage. Here, we aim to demonstrate the feasibility of using FAD autofluorescence...
The development of in-situ monitoring techniques enabling the real-time acquisition of information concerning the key variables over different Escherichia coli cultivation conditions and strategies is a crucial step towards the optimization of a plasmid bioproduction process. This work shows the use of a Near-InfraRed (NIR) fiber optic probe immersed in the culture broth for the real-time acquisition...
Batteries are crucial for most of bio applications. Batteries based on a liquid or polymer electrolyte needs a weight protective packaging which decreases their energy density and increases their size. This paper aims to identify, on the one hand, the efforts performed in thin-film batteries until now, and on the other hand, to provide an overview about the future perspectives in integration of batteries...
Alzheimer's disease is a neurodegenerative pathology characterized by extracellular accumulation of senile plaques, intracellular appearance of neurofibrillary tangles and neuronal loss. The amyloid beta-peptide soluble oligomers may have an important role in the Alzheimer's disease pathology. The current diagnostic procedures of Alzheimer's disease are difficult and are made in an advanced stage...
A direct arterial pressure monitoring system for post EVAR procedure based on inductive-coupling is presented which avoids the need for more complex biomedical imaging systems. Post stent-graft implantation complications, such as endoleaks, can be detected with capacitive pressure sensors placed in the stent-graft and monitored externally after the measurement of the oscillation frequency of a LC...
Brain-computer interfaces can be used in disabled people to accelerate recovery and improve interaction ability with the surrounding environment, helping them to achieve a better quality of life. The system proposed in this paper integrates a motion control strategy for a prosthetic arm, based on the acquisition and processing of EEG signals provided by a commercial 16-electrode headset. The acquired...
Although several studies show the clinical effectiveness of low level laser therapy (LLLT) in facilitating the muscle healing process, scientific evidence is still required to prove the effectiveness of LLLT and to clarify the cellular and molecular mechanisms triggered by irradiation of injured tissue with laser radiation. Here we evaluate the effect of different LLLT doses, using continuous illumination...
Optical Coherence Tomography (OCT) is a medical imaging technique mostly used in ophthalmology that has been developed since early 1990s. Based on optical interferometry it is capable of producing high-resolution cross-sectional images of non-homogeneous tissues such as the ocular retina. Our goal is to develop a high speed OCT for retinal imaging in small animals. This will be a fundamental tool...
In hospitals, typical tasks of delivering goods between different locations are usually done by auxiliary staff. With the development of robotic technologies, such tasks can be performed by mobile robots releasing the staff effort to other tasks. In order to successfully complete the tasks of delivering goods inside hospitals, mobile robots should be able to generate trajectories free of collisions...
Radio-frequency (RF) applications are extremely common in current days, and the extension of its use to the medical field is constantly in development. One such application is the contactless and non-invasive detection of Respiratory Rate (RR). A two-antenna RF system was developed based on the measurement of the attenuation suffered by RF waves when they cross the thorax or are reflected by the chest...
This paper presents a determining mathematical model of the slice to be removed from the human heart patients with Dilated Cardiomyopathy in the surgical process called Partial Ventriculectomy or Batista surgery. The model is based on the use of techniques of integral and differential calculus for determining the left ventricle surface area of patients with and without the disease, and calculating...
With the appearance of new teaching/learning methods, innovative techniques have been used to motivate and to improve students' skills in the area of engineering. Nowadays, remote laboratories are well accepted and used to support the students' learning in higher education, playing an important role in engineering teaching, since they allow the connection between theory and practice to all students...
Optical Coherence Tomography, OCT, is a relatively recent imaging technique that allows high resolution imaging of the retina. It relies in certain optical characteristics of light to provide information of the eye fundus, facilitating the diagnosis of certain eye pathologies. Our goal is to build a mathematical model that describes the electromagnetic wave's propagation through the eye's structures,...
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