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The Laboratory of Molecular Imaging and Nanomedicine (LOMIN) was initiated in 2009 at the Intramural Research Program of the National Institute of Biomedical Imaging and Bioengineering and has been led by Xiaoyuan (Shawn) Chen. Currently, LOMIN has grown to over 25 members who work together in diverse fields to develop theranostic molecular imaging tools and drug delivery systems. LOMIN is an interdisciplinary...
Summary form only given. The design of smart functional nanosystems for theranostics requires a thorough understanding of the interaction between nanoparticles (NPs) and biological systems. Recent observations suggest that physical parameters of NPs, like size, shape and surface charge, can dramatically affect the behaviors of NPs in biological systems and might, in part, determine the bioapplications...
The following topics are dealt with: biosensors; biochips; biomedical electronics; nanomedicine; bioinformatics; medical image processing; and genomics.
History has witnessed an enormous progress of developing nanocrystals into “smart” probes for either imaging or therapeutic applications. Such progress is in large part powered by our ability to manipulate the surface of nanoparticles, marked by the establishment of surface engineering techniques that permit facile docking of functional motifs onto particles. However, these techniques have been increasingly...
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