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A new kind of microelectrode array is presented that uses an arrangement of microfluidic channels filled with an electrolyte solution as electrodes. This allows for the spatially resolved, long term application of direct currents to cells in a culture medium on the chip. A crucial task in the production of the chip is the integration of a nanoporous polymer membrane that acts as a basis for cell adhesion...
This paper presents a novel technology to pattern polymer material deposited onto 2D and 3D surfaces at the micro- and mesoscopic scales. Electro-hydrodynamic instability patterning (EHDIP) relies on the formation of features induced by electrostatic pressure. Unlike previous work reported elsewhere in nano-patterning, we focused on the fabrication of structures from the micro- to the meso-scale....
This paper presents the challenges encountered in modelling biofluids in microchannels. In particular blood separation implemented in a T-microchannel device is analysed. Microfluids behave different from the counterparts in the microscale and a different approach has been adopted here to model them, which emphasize the roles of viscous forces, high shear rate performance and particle interaction...
A new generation of portable bio-analytical instruments is emerging, in which the analysis is carried out without any (or only minimal) intervention from the operator. To achieve this goal, the system needs to integrate both microfluidics and micro-electronics. The microfluildics are used to extract the sample (bacteria, cells, DNA, etc), carry out the bio-chemistry and deliver the sample to the detector...
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