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CNRS UMR 319, Institut de Biologie de Lille, BP447, 1 rue Calmette, 59021 Lille cedex, France Laboratoire de Biologie du Développement, Université des Sciences et Technologies de Lille, 59655 Villeneuve d'Ascq cedex, FranceThe Erg gene belongs to the Ets family encoding a class of transcription factors. To gain new insight on the in vivo functional specificity of the Erg gene within the wide Ets family, we used in situ hybridization to determine its expression pattern during murine embryogenesis. We found that the Erg gene expression predominates in mesodermal tissues, including the endothelial, precartilaginous and urogenital areas. A specific Erg gene expression was also identified in migrating neural crest cells. A comparison with Fli-1, the most closely Erg-related gene, revealed that both gene expressions partially overlap, suggesting that they may contribute to related functions in these tissues. Like other Ets family genes, Erg seems involved in several fundamental developmental steps in murine embryogenesis, including epithelio-mesenchymal transition, cell migration, settlement and differentiation.Ets familyErg and Fli-1 genesGene expressionMurine embryogenesis
CNRS UMR 319, Institut de Biologie de Lille, BP447, 1 rue Calmette, 59021 Lille cedex, France Laboratoire de Biologie du Développement, Université des Sciences et Technologies de Lille, 59655 Villeneuve d'Ascq cedex, FranceThe Erg gene belongs to the Ets family encoding a class of transcription factors. To gain new insight on the in vivo functional specificity of the Erg gene within the wide Ets family, we used in situ hybridization to determine its expression pattern during murine embryogenesis. We found that the Erg gene expression predominates in mesodermal tissues, including the endothelial, precartilaginous and urogenital areas. A specific Erg gene expression was also identified in migrating neural crest cells. A comparison with Fli-1, the most closely Erg-related gene, revealed that both gene expressions partially overlap, suggesting that they may contribute to related functions in these tissues. Like other Ets family genes, Erg seems involved in several fundamental developmental steps in murine embryogenesis, including epithelio-mesenchymal transition, cell migration, settlement and differentiation.Ets familyErg and Fli-1 genesGene expressionMurine embryogenesis
CNRS UMR 319, Institut de Biologie de Lille, BP447, 1 rue Calmette, 59021 Lille cedex, France Laboratoire de Biologie du Développement, Université des Sciences et Technologies de Lille, 59655 Villeneuve d'Ascq cedex, FranceThe Erg gene belongs to the Ets family encoding a class of transcription factors. To gain new insight on the in vivo functional specificity of the Erg gene within the wide Ets family, we used in situ hybridization to determine its expression pattern during murine embryogenesis. We found that the Erg gene expression predominates in mesodermal tissues, including the endothelial, precartilaginous and urogenital areas. A specific Erg gene expression was also identified in migrating neural crest cells. A comparison with Fli-1, the most closely Erg-related gene, revealed that both gene expressions partially overlap, suggesting that they may contribute to related functions in these tissues. Like other Ets family genes, Erg seems involved in several fundamental developmental steps in murine embryogenesis, including epithelio-mesenchymal transition, cell migration, settlement and differentiation.Ets familyErg and Fli-1 genesGene expressionMurine embryogenesis
CNRS UMR 319, Institut de Biologie de Lille, BP447, 1 rue Calmette, 59021 Lille cedex, France Laboratoire de Biologie du Développement, Université des Sciences et Technologies de Lille, 59655 Villeneuve d'Ascq cedex, FranceThe Erg gene belongs to the Ets family encoding a class of transcription factors. To gain new insight on the in vivo functional specificity of the Erg gene within the wide Ets family, we used in situ hybridization to determine its expression pattern during murine embryogenesis. We found that the Erg gene expression predominates in mesodermal tissues, including the endothelial, precartilaginous and urogenital areas. A specific Erg gene expression was also identified in migrating neural crest cells. A comparison with Fli-1, the most closely Erg-related gene, revealed that both gene expressions partially overlap, suggesting that they may contribute to related functions in these tissues. Like other Ets family genes, Erg seems involved in several fundamental developmental steps in murine embryogenesis, including epithelio-mesenchymal transition, cell migration, settlement and differentiation.Ets familyErg and Fli-1 genesGene expressionMurine embryogenesis
CNRS UMR 319, Institut de Biologie de Lille, BP447, 1 rue Calmette, 59021 Lille cedex, France Laboratoire de Biologie du Développement, Université des Sciences et Technologies de Lille, 59655 Villeneuve d'Ascq cedex, FranceThe Erg gene belongs to the Ets family encoding a class of transcription factors. To gain new insight on the in vivo functional specificity of the Erg gene within the wide Ets family, we used in situ hybridization to determine its expression pattern during murine embryogenesis. We found that the Erg gene expression predominates in mesodermal tissues, including the endothelial, precartilaginous and urogenital areas. A specific Erg gene expression was also identified in migrating neural crest cells. A comparison with Fli-1, the most closely Erg-related gene, revealed that both gene expressions partially overlap, suggesting that they may contribute to related functions in these tissues. Like other Ets family genes, Erg seems involved in several fundamental developmental steps in murine embryogenesis, including epithelio-mesenchymal transition, cell migration, settlement and differentiation.Ets familyErg and Fli-1 genesGene expressionMurine embryogenesis