Two new 7,20-epoxy-ent-kaurenoids, enanderianin A and B, were isolated from the leaves of Isodon enanderianus and identified on the basis of spectroscopic methods. The structures of the new compounds were established at 1β,6β,7β-trihydroxy-11α,19-diacetoxy-7α,20-epoxy-ent-kaur-16-en-15-one and 1β,6β,7β,11α-tetrahydroxy-19-acetoxy-7α,20-epoxy-ent-kaur-16-en-15-one.