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Meta Gene publishes meta-analysis, polymorphism and population study papers that are relevant to both human and non-human species. Examples include but are not limited to:
Cone-Rod Dystrophies (CRDs) are pigmentary retinopathies predominantly involving the macular cone photoreceptors leading to visual loss at an early age. Mutation analysis, especially in syndromic forms helps with diagnosis and disease management as well as prevention using preimplantation or prenatal diagnosis. However, it is hampered by genetic heterogeneity of CRDs. Here we report on successful...
Previous reports clearly suggest that IL-17 have important role in development of systemic and peripheral inflammation in early miscarriage (EM). In the present study, we have investigated the association between genetic variants in IL-17A, IL-17F and susceptibility to EM. We recruited 135 EM patients and 150 controls and used PCR-RFLP method for genotyping the polymorphisms of IL-17A, rs4711998 (−832...
We conducted the current meta-analysis to quantitatively summarize the evidence for the strength of the associations between 4-bp insertion/deletion (I/D) polymorphism (rs10680577) of EGLN2 and cancer risk. Using databases searches, we included 5 case-control studies encompassing 3030 cases and 4728 controls. The pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. The findings...