AgIn 5 Te 8 was synthesized by melting reaction method, the electrical and thermal transport properties have been evaluated along the directions parallel and perpendicular to the ingot growth direction. Both electrical and thermal transport properties show the anisotropic characteristics. The electrical and thermal conductivities along the perpendicular direction are higher than that of parallel one. The large band gap of about 1.0eV determines a low electrical conductivity. The T −1 dependence of diffusivity for AgIn 5 Te 8 suggests a phonon dominant transport behavior, consistent with the insulating character of the electrical transport properties. AgIn 5 Te 8 owns intrinsically low thermal conductivity, which decreases with increasing temperature, from 1.1Wm −1 K −1 and 0.95Wm −1 K −1 at room temperature to 0.5Wm −1 K −1 and 0.4Wm −1 K −1 at 873K for AgIn 5 Te 8 along perpendicular and parallel directions, respectively. This low thermal conductivity for AgIn 5 Te 8 demonstrates this system could be promising for thermoelectric applications by improving electrical transport properties through tuning carrier concentrations.