We have previously shown that repetitive doses of erythemogenic UVA and solar-simulated UV and sub-erythemogenic UVA are capable of inducing significant changes in previously non sun-exposed buttock skin. Most notable of these findings were the unexpected morphologic alterations produced by the suberythemogenic UVA and observed after only 12 weeks of twice weekly irradiation. Upon reexamination of this skin two years after the final irradiation, we observed significant pigmentation, fine line wrinkling and atrophy. Upon histopathologic examination, we observed that although marked pigmentation was present, the epidermis displayed a normal morphology. In addition, perivascular infiltrate and vascular dilation were evident in the dermis. Elastotic tissue was also apparent in the dermis of irradiated tissue, and image analysis quantification of elastic tissue showed increases in all irradiated tissue. Our latest findings suggest that UV irradiation has a greater and longer lasting effect on the morphology of the dermis as compared to the epidermis. In addition, our findings indicate that even small doses of UV irradiation can produce changes which can persist for at least several years. Our results also demonstrate that even suberythemogenic doses of UVA, to which the public is easily exposed, are capable of producing significant and lasting changes in the skin.