Extensive studies have been carried out to identify plant proteins with insecticidal properties towards insects. The paper describes a test for screening toxicity and growth inhibition of five commercially available proteins such as: bromelain, honey bee venom, two lectins-wheat germ agglutinin (WGA), concanavalin A (Con A) and lysozyme in artificial diets on Sitobion avenae /F./. Grain aphid proved to be sensitive to all tested proteins. Among the tested proteins concanavalin A and wheat germ agglutinin had the highest negative influence on feeding, reduced weight and increased mortality of tested aphids independently from the dose. It suggested that this group of the proteins have an insecticidal activity and is a good candidate for control of the insect pests.