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Hepatitis B virus (HBV) infection in the United States is the most common among Asians followed by non‐Hispanic blacks. However, there have been few studies that describe HBV infection and immunity by racial group. Our study aimed to assess racial/ethnic disparities in the prevalence and awareness of HBV infection and immunity using nationally representative data. In the National Health and Nutrition...
We investigated soluble human leukocyte antigen‐G (sHLA‐G) expression according to the phases of hepatitis B virus (HBV) infections and hepatocellular carcinoma (HCC). A total of 267 sera from anti‐HBs positive healthy individuals (n = 50), chronic HBV carriers (n = 45), as well as patients with active hepatitis B (n = 46), liver cirrhosis (LC, n = 46) and early stage HCC (n = 80) were collected and...
In an attempt to develop an edible vaccine, we transformed a recombinant hepatitisBvirus (HBV) gene encoding the middle protein of HBV that contains the surface S and preS2antigen into potato by Agrobacterium-mediated transformation. The HBV gene was under control of either the CaMV35S promoter, the double35S promoter with the AlMV 5non-translated leader sequence, or the tuber-specific patatin promoter...
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