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Synthetic diacylglycerol lactones (DAG lactones) are effective modulators of critical cellular signaling pathways downstream of the lipophilic second messenger diacylglycerol that activate a host of protein kinase C (PKC) isozymes as well as other non‐kinase proteins that share with PKC similar C1 membrane‐targeting domains. A fundamental determinant of the biological activity of these amphiphilic...
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