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The presence of lymphocytic infiltration (LI) has been correlated with nodal metastasis and tumor recurrence in HER2+ breast cancer (BC). The ability to automatically detect and quantify extent of LI on histopathology imagery could potentially result in the development of an image based prognostic tool for human epidermal growth factor receptor-2 (HER2+) BC patients. Lymphocyte segmentation in hematoxylin...
The presence of lymphocytic infiltration (LI) has been correlated with nodal metastasis and tumor recurrence in HER2+breast cancer (BC), making it important to study LI. The ability to detect and quantify extent of LI could serve as an image based prognostic tool for HER2+ BC patients. Lymphocyte segmentation in H & E-stained BC histopathology images is, however, complicated due to the similarity...
Accurate extraction of contour information from neural stem cells is important, as the shapes of neural stem cells may contain significant features for studying their activities in time lapse image sequences especially during their cleavage. In this paper, an algorithm is presented for this purpose. Fuzzy threshold method based on Zadeh's maximum entropy is adopted for cell segmentation. The best...
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