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Like all other parts of the central nervous system, the mammalian neocortex undergoes temporally ordered set of developmental events, including proliferation, differentiation, migration, cellular identity, synaptogenesis, connectivity formation, and plasticity changes. These neurodevelopmental mechanisms have been characterized by studies focused on transcriptional control. Recent findings, however,...
Von Economo neurons (VENs) are modified pyramidal neurons characterized by an extremely elongated rod‐shaped soma. They are abundant in layer V of the anterior cingulate cortex (ACC) and fronto‐insular cortex (FI) of the human brain, and have long been described as a human‐specific neuron type. Recently, VENs have been reported in the ACC of apes and the FI of macaque monkeys. The first description...
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