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Background There have been several reports of patients experiencing cerebral embolisms following the injection of autologous fat into the face during cosmetic surgery. These embolisms likely resulted from unintentional introduction of fat particles into facial arteries, which then reached the cerebral arteries by retrograde motion. Case Presentation We describe here a patient who developed an internal...
Blocking histamine H3 receptor leads to increased histamine in the brain. The effects of H3 receptor antagonist in the rat model of neonatal hypoxic-ischemic encephalopathy (NHIE) and its mechanism is uncertain. In our study, we employed a NHIE model of postnatal 7 days rats and tested the brain water content, hippocampal histamine, cerebral MDA and SOD levels under the different combinations of H1,...
Apert syndrome is a rare congenital type I acrocephalosyndanctyly syndrome, characterized by craniosynostosis, severe syndactyly of the hands and feet, symphalangism and dysmorphic facial features. Here we reported one case of Apert syndrome and reviewed the literature. This patient presented with the clinical triad that characterized Apert syndrome: brachycephalic skull, midface hypoplasia and syndactyly...
Infantile spasms (IS) is an age-related epileptic disorder characterized by specific spasms, hypsarrhythmia and mental retardation. Most of IS patients can not get spasm free under the available treatment and prognosis is poor. It is crucial to develop new effective drugs the treatment of IS. Histamine H3 receptor antagonist seems to be effective in some epilepsy models. Betahistine is one of H3 antagonists...
In order to explore the effects of initial polytherapy by combining ACTH followed by prednisone, topiramate, IVIG and vitamin B6 in newly diagnosed West syndrome. 51 children with West syndrome were included in our study. Forty-six patients became spasm-free through polytheray, two children effective and three ineffective. Statistical difference in time to spasm free was found between cryptogenetic...
Alice in wonderland syndrome is associated with migraine, epilepsy, infectious mononucleosis, Epstein-Barre viral infection and psychological disorders. It has rarely been reported in children. We report one case of pediatric migraine with onset as AIWS. A 13 years-old boy who experienced paroxysmal visual illusions for 6 years and headaches for 1 year. The child was previously misdiagnosed as pediatric...
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