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We present a second near‐infrared (NIR‐II) self‐checking molecule, LET‐1052, for acidic tumor microenvironment (TME) turn‐on photothermal therapy (PTT), followed by viscosity based therapeutic efficacy evaluation by itself in two independent channels, denoted as “self‐checking” strategy. In acidic TME, LET‐1052 was protonated and turned on NIR‐II absorption for PTT under 1064 nm laser irradiation...
We present a second near‐infrared (NIR‐II) self‐checking molecule, LET‐1052, for acidic tumor microenvironment (TME) turn‐on photothermal therapy (PTT), followed by viscosity based therapeutic efficacy evaluation by itself in two independent channels, denoted as “self‐checking” strategy. In acidic TME, LET‐1052 was protonated and turned on NIR‐II absorption for PTT under 1064 nm laser irradiation...
In this poster, unique nanobioconjugation techniques to produce targeted nanoprobes with high fluorescence activation, establishing a highly enhanced fluorescence sensor system are presented. By diversifying conjugation styles to the AuNP surface, a ratio of targeting agents and dyes can be achieved for 100 time fold activation. Conjugation of fluorescence dyes for quenching is dependent on access...
Summary form only given. Ferritin is a family of proteins found in different forms in most living organisms. Each ferritin is made up of 24 subunits, which self-assemble to form a cage-like nanostructure, with external and internal diameters of 12 and 8 nm, respectively. This unique architecture provides two interfaces-one outside and one inside-for possible functional loading. These interesting features...
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