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Background
Isavuconazole, administered as isavuconazonium sulfate (ISAVUSULF), is a broad‐spectrum triazole agent for the treatment of invasive fungal disease. In phase 3 studies, ISAVUSULF showed comparable efficacy to voriconazole and amphotericin B for the treatment of invasive aspergillosis (IA) and invasive mucormycosis (IM), respectively.
Objectives
The objective of this study is to determine...
Background
Current guidelines recommend oral vancomycin or fidaxomicin for the treatment of mild‐to‐moderate Clostridium difficile associated diarrhea (CDAD), while metronidazole is recommended as an alternative when oral vancomycin and fidaxomicin are unavailable. However, data are lacking among the solid organ transplant (SOT) population.
Methods
This single center, retrospective cohort study...
Background Treatment of complicated skin and skin structure infection (cSSSI) places a tremendous burden on the health care system. Understanding relative resource utilization associated with different antimicrobials is important for decision making by patients, health care providers, and payers. Methods The authors conducted an open-label, pragmatic, randomized (1:1) clinical study (N = 250) to...
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