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Immunocheckpoint inhibitors combined with Lenvatinib is the first line treatment for hepatocellular carcinoma (HCC), but their potency is hampered by the low response rate and adverse events. Herein, a targeted therapeutic strategy through the coassembly of Lenvatinib, Adriamycin, Fe3+ ion, and a natural polyphenol (metallo‐nanodrugs) is presented by coordination effect for potentiating tumor vascular...
In this paper, silica nanoparticles (SiO2) were modified by using esterification and a large-area monolayer of SiO2 nanoparticles was fabricated by using the Langmuir–Blodgett (LB) assembly technique. Then, a layer of gold nanoshell was sprayed at this monolayer film to obtain a large-area SiO2/Au core–shell nanostructure for surface-enhanced Raman scattering (SERS). The synthesized SiO2 were characterized...
The paper proves the feasibility of using the ultrafiltration combined with reverse osmosis to desalt sea water in Bohai Bay over four-month pilot running. The results show that the influent quality is not influenced by the UF effluent quality and the optimum operational parameters are the flux 62.5 L/m2·h, the quality of UF permeate was excellent, with turbidity measured below 0.13 NTU and 94% of...
According to the characteristics of water quality in Tianjin Bohai Bay, ultrafiltration (UF) pretreatments prior to SWRO without any chemicals and with coagulation were studied. Under the same operational and cleaning conditions, two pilot tests were discussed through monitoring and analyzing water quality, assessment of flux and transmembrane pressure. The study showed that both of the UF pretreatment...
D-matrix is the basement of large-scale-system equipment test and diagnosis. In order to cover the shortage of D-matrix information in TEAMS model construction, Advanced D-matrix is proposed, reflecting the nature of Equipment and solving the problem that could cause confusion in signal invalidation of D-matrix fault definition. A method to get advanced D-matrix data from multi-signal model is given...
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