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Complex 3D artificial tissue constructs are extensively investigated for tissue regeneration. Frequently, materials and cells are delivered separately without benefitting from the synergistic effect of combined administration. Cell delivery inside a material construct provides the cells with a supportive environment by presenting biochemical, mechanical, and structural signals to direct cell behavior...
In article number 1702207, Laura De Laporte and co‐workers report a novel anisotropic injectable hydrogel that promotes unidirectional nerve growth in a 3D microenvironment. The hybrid hydrogel comprises short magneto‐responsive fibers, which are produced via an electrospinning/cryocutting method. After injection, they orient in a low external magnetic field, while the hydrogel crosslinks to fix the...
To regenerate soft aligned tissues in living organisms, low invasive biomaterials are required to create 3D microenvironments with a structural complexity to mimic the tissue's native architecture. Here, a tunable injectable hydrogel is reported, which allows precise engineering of the construct's anisotropy in situ. This material is defined as an Anisogel, representing a new type of tissue regenerative...
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