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SARS‐CoV‐2 is the coronavirus responsible for the COVID‐19 pandemic. Proteases are central to the infection process of SARS‐CoV‐2. Cleavage of the spike protein on the virus's capsid causes the conformational change that leads to membrane fusion and viral entry into the target cell. Since inhibition of one protease, even the dominant protease like TMPRSS2, may not be sufficient to block SARS‐CoV‐2...
The effects of infraorbital nerve (ION) transection on gene expression in the adult female rat barrel cortex were investigated using RNA sequencing. After a 24‐hour survival duration, 28 genes were differentially regulated by ION transection. Differentially expressed genes suggest microglial activity, increased retrograde ciliary transport, and a decrease in inhibition. These changes may be functionally...
This paper mainly brings out the details related to a prototype biodiversity information retrieval system that has been setup using the distributed Grid-Cloud resources of GARUDA Grid project, India. The overall experiment has been done with the help of open source biodiversity databases. The structure of these relational database tables are not standardized and are hosted on a variety of Database...
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