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Background
Acute chest syndrome (ACS) is a leading cause of morbidity and mortality among children with sickle cell disease (SCD). Preventing hypoxemia by optimizing lung aeration during sleep remains a challenge.
Objectives
To explore safety, feasibility, and tolerability of noninvasive, bi‐level positive airway pressure ventilation (BiPAP) as preventative, supportive care for hospitalized, medically...