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Background
Glioblastoma (GBM) is the most common malignant primary brain tumor. Emerging reports have suggested that racial and socioeconomic disparities influence the outcomes of patients with GBM. No studies to date have investigated these disparities controlling for isocitrate dehydrogenase (IDH) mutation and O‐6‐methylguanine‐DNA methyltransferase (MGMT) status.
Methods
Adult patients with...
Background
Effective treatment for pediatric embryonal brain tumors includes dose‐intensive multiagent chemotherapy (DIMAC) followed by high‐dose chemotherapy with stem cell rescue (HDCSCR). Use of repeated cycles of DIMAC including high‐dose methotrexate (HDMTX) without HDCSCR has not been described.
Procedure
We retrospectively reviewed the responses/toxicities in 13 patients (aged 2‐155 months,...
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