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Purpose
To develop a high spatiotemporal resolution 3D dynamic pulse sequence for preclinical imaging of hyperpolarized [1‐13C]pyruvate‐to‐[1‐13C]lactate metabolism at 7T.
Methods
A standard 3D balanced SSFP (bSSFP) sequence was modified to enable alternating‐frequency excitations. RF pulses with 2.33 ms duration and 900 Hz FWHM were placed off‐resonance of the target metabolites, [1‐13C]pyruvate...
The aim of this study was to acquire the transient MRI signal of hyperpolarized tracers and their metabolites efficiently, for which specialized imaging sequences are required. In this work, a multi‐echo balanced steady‐state free precession (me‐bSSFP) sequence with Iterative Decomposition with Echo Asymmetry and Least squares estimation (IDEAL) reconstruction was implemented on a clinical 3 T positron‐emission...
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