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Aim
This study aimed to investigate and verify the effect of cell‐penetrating peptide (CPP)‐conjugated soluble N‐ethylmaleimide‐sensitive factor attachment protein receptor (SNARE) motif of vesicle‐associated membrane protein 2 (VAMP2)‐patterned peptide (INCI name: Acetyl sh‐Oligopeptide‐26 sh‐Oligopeptide‐27 SP, trade name: M.Biome‐BT) on improving skin function in vitro.
Methods
The cytotoxicity...
Background
Catechol‐containing polymers such as mussel adhesive proteins (MAPs) are attractive as biocompatible adhesive biomaterials, and the catecholic amino acid 3,4‐dihydroxyphenyl‐L‐alanine (DOPA) is considered a key molecule in underwater mussel adhesion. Tyrosinases can specifically convert tyrosine to DOPA without any cofactors. However, their catalytic properties still need to be adjusted...
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