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Background and Objectives
Graft failure (GF) after cord blood transplant (CBT) has decreased with improved supportive care and cord selection strategies. We aimed to evaluate cord blood selection and factors associated with retransplantation on the incidence of GF, determine risk factors for GF including host antibodies to Kell antigen and evaluate survival after GF.
Materials and Methods
We retrospectively...
Cyclosporine is commonly used as an immunosuppressive agent in both solid organ and bone marrow transplant. While used for graft rejection in organ transplantation, cyclosporine has been used to enable tolerance and for prevention of acute graft‐versus‐host disease in bone marrow transplant [Ratanatharathorn et al., Blood 1998;92:2303–2314]. Cyclosporine has a narrow therapeutic window, and many patients...
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