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Bisphenol S (BPS) is an environmental endocrine disruptor widely used in industrial production. BPS induces oxidative stress and exhibits male reproductive toxicity in mice, but the mechanisms by which BPS impairs steroid hormone synthesis are not fully understood. Nuclear factor erythroid 2‐related factor 2(Nrf2)/HO‐1 signaling is a key pathway in improving cellular antioxidant defense capacities...