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The impact of the interaction between NK cells and lung dendritic cells (LDCs) on the outcome of respiratory infections is poorly understood. In this study, we investigated the effect and mechanism of NK cells on the function of LDCs during intracellular bacterial lung infection of Chlamydia muridarum in mice. We found that the naive mice receiving LDCs from C. muridarum‐infected NK‐cell‐depleted...
Natural killer T (NKT) cells are a newly identified T‐cell population with potential immunomodulatory functions. Several studies have shown modulating effects of NKT cells activated by α‐galactosylceramide, a model antigen, on NK cell function. We here report a differential modulating effect of NKT cells on the interferon‐γ (IFN‐γ) production and cytolytic function of NK cells in a chlamydial infection...
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