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Background
Accumulating evidence links COVID‐19 incidence and outcomes with vitamin D status. We investigated if an interaction existed between vitamin D levels and social deprivation in those with and without COVID‐19 infection.
Methods
Upper or lower respiratory tract samples from 104 patients were tested for SARS‐CoV‐2 RNA in accordance with Public Health England criteria (January‐May 2020)...
CD6 is a type I T‐cell surface receptor that modulates antigen receptor signalling. Its activity is regulated by binding of its membrane proximal domain (domain 3) to a cell surface ligand, CD166. CD6 monoclonal antibodies (mAbs) specific for the membrane distal domain (domain 1) perturb CD6 function including itolizumab (Alzumab™), which has reached the clinic for treatment of autoimmune disease...
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