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Primycin-sulphate is a highly effective compound against Gram (G) positive bacteria. It has a potentially synergistic effect with vancomycin and statins which makes primycin-sulphate a potentially very effective preparation. Primycin-sulphate is currently used exclusively in topical preparations. In vitro animal hepatocyte and neuromuscular junction studies (in mice, rats, snakes, frogs) as well as...
AimTo establish whether eliminating Lysyl oxidase (LOX) gene would affect dentine formation.
MethodologyNewborn wild‐type (wt) and homo‐ and heterozygous LOX knock‐out (Lox−/− and Lox+/−, respectively) mice were used to study developing tooth morphology and dentine formation. Collagen aggregation in the developing dentine was examined histochemically with picrosirius red (PSR) staining followed by...
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