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This study explored the impact of developmental stage on cognitive function in children with recently-diagnosed epilepsy. In keeping with a neurodevelopmental framework, skills in a critical developmental period were expected to be more vulnerable than those stable at the time of seizure onset. We studied children with early-onset (EO) symptomatic focal epilepsy (onset: 3–5years; n=18) and compared...
Purpose: To assess the impact of childhood‐onset temporal lobe epilepsy (TLE) on the attainment of normative developmental tasks and identify predictors of long‐term developmental outcomes.
Methods: In 1992–1993, a prospective longitudinal cohort study of childhood‐onset TLE was commenced in the State of Victoria, Australia. At review in 2004–2006, we assessed developmental tasks, which are age‐specific...
Purpose Single-suture craniosynostosis (SSC) is a congenital craniofacial disorder, in which premature fusion of one of the skull sutures restricts and distorts growth of the cranium and underlying brain. This disorder of prenatal onset occurs during a critical phase of rapid growth and development of the immature brain. Craniosynostosis carries a known risk of developmental impairment. The neurodevelopmental...
Purpose: To examine the effect of childhood‐onset temporal lobe epilepsy (TLE) on long‐term psychological function and to identify outcome profiles related to the natural course and treatment of TLE.
Methods: Psychological function was studied in a prospective, community‐based cohort of childhood‐onset TLE, approximately 13 years following seizure onset. Fifty‐three patients were assessed using...
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