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Background and purposeTo compare the course of treatment in patients with symptomatic Wilson's disease (WD) receiving either D‐penicillamine (DPA) or zinc sulfate (ZS) as first‐line therapy.
MethodsIn all, 143 consecutive patients diagnosed with symptomatic WD from January 2005 to December 2009, followed until December 2010, were included. The decision about first‐line therapy was made individually...
Background and purposeWilson's disease (WD) is an inherited copper metabolism disorder that leads to dysfunction of affected tissues, mostly in the liver and brain. Anti‐copper treatment should prevent clinically overt WD in pre‐symptomatic patients but this has not been supported by strong evidence. Our aim was to evaluate the long‐term effectiveness of treatment in clinically pre‐symptomatic patients,...
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