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Background
Pronounced asymmetric changes in ocular globe size during eye development have been observed in a number of species ranging from humans to lizards. In contrast, largely symmetric changes in globe size have been described for other species like rodents. We propose that asymmetric changes in the three‐dimensional structure of the developing eye correlate with the types of retinal remodeling...
The roles of endothelin-1 (ET-1) and its receptors (ET A , ET B ) in mediating altered arterial reactivity in arteries undergoing atherosclerotic changes and/or collateral hyperperfusion, processes of occlusive arterial disease, were evaluated in isolated arteries. Use of normo- (C-) and hypercholesterolemic rabbits (C+) with normal (F-) or high carotid artery flows (F+) induced by...
The influence of atherosclerosis on vascular growth in humans was evaluated in an in vitro model of angiogenesis. Coronary artery intima-media explants from patients (n = 10) with coronary artery disease (CAD) (in all cases Stary type V lesions) and patients without CAD (n = 10) were cultured in a collagen matrix containing serum-free medium. Endothelial cell growth from explants was organized as...
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