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Several studies observed that adiponectin, an important adipokine that improves glucose metabolism by regulating AMP‐activated protein kinase (AMPK) signaling, is dermatologically beneficial. In our recent microarray data, we found that adiponectin expression was lower in lesional skin than in non‐lesional skin of melasma patients. Given that AMPK is a key adiponectin signaling mediator, we investigated...
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