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Background Information
Like most other cell surface proteins, α5β1 integrin is glycosylated, which is required for its various activities in ways that mostly remain to be determined.
Results
Here, we have established the first comprehensive site‐specific glycan map of α5β1 integrin that was purified from a natural source, that is, rat liver. This analysis revealed striking site selective variations...
Tc (toxin complex) toxins are virulence factors of many insect- and human-pathogenic bacteria. They are composed of three subunits that act together to perforate the host membrane using a syringe-like injection mechanism. Thereby they translocate toxic enzymes into the cell, resulting ultimately in the death of the host cell. Our recent high-resolution structural and functional data explain the mechanism...
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