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Frailty models are the possible choice to counter the problem of the unobserved heterogeneity in individual risks of disease and death. Based on earlier studies, shared frailty models can be utilised in the analysis of bivariate data related to survival times (e.g. matched pairs experiments, twin or family data). In this article, we assume that frailty acts additively to the hazard rate. A new class...
Most of the important genomic regions, especially the G,C rich gene promoters, consist of sequences with potential to form G,C‐tetraplexes on both the DNA strands. In this study, we used three C‐rich oligonucleotides (11Py, 21Py, and HTPy), of which 11Py and 21Py are located at various transcriptional regulatory elements of the human genome while HTPy sequence is a C‐rich strand of human telomere...
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