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ObjectiveThe aim of this study was to evaluate the combination of bupivacaine and methadone administered epidurally in sheep.
MethodsSix healthy female mixed‐breed sheep weighing 35–46 kg and aged 12–18 months were included. Each sheep was assigned to receive three treatments: 0.5 mg/kg 0.25% bupivacaine (BP), 0.3 mg/kg 1% methadone (MT) or 0.25 mg/kg bupivacaine and 0.15 mg/kg methadone (BPMT). All...