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Aim
We investigated the expression of neuropeptide Y (NPY), NPY receptor 1 (NPYR1) and NPY receptor 2 (NPYR2) in infantile haemangiomas (IHs).
Methods
Immunohistochemical (IHC) staining was performed on proliferating IHs from six patients aged 4–13 (mean 8.7) months and involuted IHs from six patients aged 5–59 (mean 18.7) years, for the expression of NPY, NPYR1 and NPYR2. Protein and messenger...
AimsPropranolol, now the preferred treatment for problematic proliferating infantile haemangioma (IH), at an empirical cardiovascular dosage of 2–3 mg/kg/day is associated with variable complication rates. A meta‐analysis shows complications in 31% of patients at a mean dosage of 2.12 mg/kg/day. This study reports on the minimal dosage and duration of treatment to achieve accelerated involution and...
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