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Hepatic Ischemia‐Reperfusion Injury Management
Selenium‐doped carbon quantum dots (Se‐CQDs) with excellent anti‐oxidation capability protect hepatocytes from apoptosis by limiting damage from oxidative stress. Se‐CQDs‐lecithin nanoparticles are developed through a supramolecular self‐assembly mainly driven by noncovalent interactions, which effectively scavenge reactive oxygen species and inhibit...
Hepatic ischemia‐reperfusion injury (HIRI) is a critical complication after liver surgery that negatively affects surgical outcomes of patients with the end‐stage liver‐related disease. Reactive oxygen species (ROS) are responsible for the development of ischemia‐reperfusion injury and eventually lead to hepatic dysfunction. Selenium‐doped carbon quantum dots (Se‐CQDs) with an excellent redox‐responsive...
Lysophosphatidylcholine acyltransferase‐1 (LPCAT1) plays a critical role in the remodeling of phosphatidylcholines (PCs) in cellular lipidome. However, evidence is scarce regarding its sn‐selectivity, viz. the preference of assembling acyl‐Coenzyme A (CoA) at the C1 or C2‐hydroxyl on a glycerol backbone because of difficulty to quantify the thus‐formed PC sn‐isomers. We have established a multiplexed...
Lysophosphatidylcholine acyltransferase‐1 (LPCAT1) plays a critical role in the remodeling of phosphatidylcholines (PCs) in cellular lipidome. However, evidence is scarce regarding its sn‐selectivity, viz. the preference of assembling acyl‐Coenzyme A (CoA) at the C1 or C2‐hydroxyl on a glycerol backbone because of difficulty to quantify the thus‐formed PC sn‐isomers. We have established a multiplexed...
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