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Background
The possible role of phosphodiesterase 5 inhibitors (PDE5Is) in prevention of negative effect of diabetes mellitus (DM) on erectile function is not well settled.
Objectives
To investigate the effect of early administration of vardenafil on erectile function, cavernosal structure, and genes expression in a rat model of DM.
Materials and methods
This experimental study was carried out...
Seminal cytokines were previously reported to adversely affect process of spermatogenesis and ultimately induce poor semen quality. However, association between both IL‐6 and TNF‐α and leukocytospermia was not yet settled. The aim of this study was to evaluate the association between leukocytospermia and levels of interleukin‐6 (IL‐6) and tumor necrosis factor‐alpha (TNF‐α) in semen of infertile men...
The association between endothelial dysfunction and late onset hypogonadism (LOH) in patients with vasculogenic erectile dysfunction (ED) is not yet well settled. Our objective was to assess the association between LOH and endothelial dysfunction in patients with vasculogenic ED. Throughout 2014–2015 a total of 90 men were enrolled in this cross‐sectional observational study. Of them 60 patients with...
Traditionally, clinical conditions synonymous with the ageing male included cardiovascular disease (CVD), type 2 diabetes mellitus (DM) and sexual dysfunction, and were widely regarded as independent clinical entities. Over the last decade, interrelationship of clinical conditions has been convincingly demonstrated. Declining testosterone levels in the elderly, once regarded as an academic endocrinological...
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