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Background
Exposure to heat waves could result in adverse effects on human health, especially in male testicles. PIWI‐interacting RNA (piRNA) is a novel type of small non‐coding RNA, which can notably impact mRNA turnover and preserve germline maintenance in germline cells. However, piRNA's expression status when adapting to testicular heat stress remains largely unclear.
Objectives
To investigate...
Ubiquitin conjugating enzyme (E2) is crucial for mediating N‐terminal ubiquitination. Recent study reports that UBE2W is involved in male infertility. However, the correlation between UBE2W expression and hypospermatogenesis is unclear. The present study is to explore the biological role of UBE2W and its association with hypospermatogenesis. Results showed that the sexpression levels of UBE2W in mouse...
Sertoli-cell only syndrome is one of the reasons for male infertility but its pathogenesis remains unclear. PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. In this study we further investigated the correlation between PRPS2 and Sertoli-cell only syndrome, and evaluated the effect of PRPS2 expression on apoptosis of TM4 Sertoli cells.PRPS2 expression...
To investigate the relationship between histopathologic patterns of testicular biopsy and biochemical semen and blood plasma parameters, including neutral a-glucosidase (NAG), fructose, follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone, and prolactin (PRL) in patients with azoospermia.A total of 471 azoospermic patients with definitive pathologic diagnosis were enrolled in...
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