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BackgroundThe relationships between tonsillar immune responses, and viral infection and allergy are incompletely known.
ObjectiveTo study intratonsillar/nasopharyngeal virus detections and in vivo expressions of T‐cell‐ and innate immune response‐specific cytokines, transcription factors, and type I/II/III interferons in human tonsils.
MethodsPalatine tonsil samples were obtained from 143 elective...
Computer science and biology have inspired each other by drawing analogies. Biological molecules are even used directly as new material building blocks for creating next generation computer hard- and software. Recently, biology is moving to larger scales, generating datasets of high complexity and size. This allows moving from studies of individual biological entities such as proteins to their complex...
Signal transduction pathways are central to most biological processes. Diversion of such pathways is postulated to be central to the mechanism by which the Human Immunodeficiency Virus-1 (HIV) takes over the human cellular machinery. In this paper, we present an analysis of the interactions between HIV and human signal transduction pathways. We find that the majority of known human pathways are targeted...
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