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Macrophages can polarize in which M1/classically activated and M2/alternatively activated macrophages are considered to be the extremes. M1 macrophages are involved in inflammatory reactions, while M2 macrophages are suggested to be involved in homeostasis, parasite killing, tumor promotion, tissue remodeling and in allergic reactions. We hypothesized that polarization of placental macrophages (Hofbauer...
To cite this article: Joerink M, Oortveld MAW, Stenius F, Rindsjö E, Alm J, Scheynius A. Lifestyle and parental allergen sensitization are reflected in the intrauterine environment at gene expression level. Allergy 2010; 65: 1282–1289.
AbstractBackground: Environmental factors, including the intrauterine environment, can influence the risk of allergy development. In the present study, we investigated...
To cite this article: Rindsjö E, Joerink M, Johansson C, Bremme K, Malmström V, Scheynius A. Maternal allergic disease does not affect the phenotype of T and B cells or the immune response to allergens in neonates. Allergy 2010; 65: 822–830.
AbstractBackground: It is hypothesized that the in utero environment in allergic mothers can affect the neonatal immune responses. The aim of this study was...
To cite this article: Rindsjö E, Joerink M, Papadogiannakis N, Scheynius A. IgE in the human placenta: why there? Allergy 2010; 65: 554–560.
AbstractImmunoglobulin E (IgE) antibodies are key effector molecules in the allergic inflammatory response and are also involved in the protection against extracellular parasites. Allergic symptoms often develop early in life, and the intrauterine environment...
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